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  • research-news-and-updates
  1. Blog

Research news and updates

The Future of Clinical Care and Research in Aplastic Anaemia: The Funding Priorities

The Future of Clinical Care and Research in Aplastic Anaemia: The Funding Priorities

The Aplastic Anaemia Trust, our Research and Clinical Advisory Panel, and Professor Ted Gordon Smith have published a report into the priorities for research and improving clinical care in rare bone marrow failure. Read more

Posted to: Research news and updates

Published: 12th November, 2025

Updated: 30th March, 2026

Improving the treatment of aplastic anaemia: what's coming next?

Improving the treatment of aplastic anaemia: what's coming next?

The last video in our little series: Given all these improvements, what should we be looking forward to in the next 40 years? Professor Gordon Smith and Dr Austin share what they're most excited about. Read more

Posted to: Research news and updates

Published: 1st April, 2025

Updated: 9th April, 2025

The progress in transplants

The progress in transplants

Prof Gordon Smith asks Dr Austin about what transplants are like for aplastic anaemia patients now, and learns about one huge advance since his day. Read more

Posted to: Research news and updates

Published: 25th March, 2025

Updated: 9th April, 2025

The beginning of The Aplastic Anaemia Trust

The beginning of The Aplastic Anaemia Trust

We learn about why The AAT started, who started it, and what that had to do with tents. Read more

Posted to: Research news and updates

Published: 18th March, 2025

Updated: 25th March, 2025

Discovering ATG

Discovering ATG

In this second video celebrating 40 years of The Aplastic Anaemia Trust, Professor Ted Gordon Smith shares what he thinks of ATG! And we learn the name of the first ATG horse... Read more

Posted to: Research news and updates

Published: 11th March, 2025

Updated: 9th April, 2025

The beginning of aplastic anaemia and its treatment.

The beginning of aplastic anaemia and its treatment.

To celebrate 40 years of The Aplastic Anaemia Trust, we invited Professor Ted Gordon Smith to Kings Hospital to meet with Dr Austin Kulasekararaj and discuss treatment for aplastic anaemia and how it has improved. In this first video, Professor Gordon Smith talks about how clinicians first started using transplant for patients with aplastic anaemia, in the mid 1970s. Read more

Posted to: Research news and updates

Published: 4th March, 2025

Updated: 9th April, 2025

Promising result from TIARA clinical trial gives new hope to patients

Promising result from TIARA clinical trial gives new hope to patients

King’s College Hospital and King’s College London are trialling cutting-edge cell therapy to develop a brand new treatment for the condition. It’s a world first - funded by The Aplastic Anaemia Trust and LifeArc. On 7th December, Dr Nazia Matto, the trial’s lead GMP production scientist presented initial findings from the TIARA trial, revealing promising results Read more

Posted to: Research news and updates

Published: 13th December, 2024

Mutation Timing and Clonal Trajectories in Aplastic Anaemia

Mutation Timing and Clonal Trajectories in Aplastic Anaemia

The Aplastic Anaemia Trust will fund a new research project, investigating genetic mutations in patients with aplastic anaemia or PNH. Read more

Posted to: Research news and updates

Published: 28th June, 2024

RACE trial: Does eltrombopag improve outcomes for severe and very severe aplastic anaemia patients?

RACE trial: Does eltrombopag improve outcomes for severe and very severe aplastic anaemia patients?

Read the new plain language summary of the RACE trial to learn more about how taking eltrombopag alongside treatment with horse ATG and ciclosporin has been shown to lead to faster treatment response for people with severe and very severe aplastic anaemia. Read more

Posted to: Research news and updates

Published: 15th December, 2023

Updated: 9th April, 2026

TIARA Clinical trial of new aplastic anaemia treatment now recruiting patients

TIARA Clinical trial of new aplastic anaemia treatment now recruiting patients

The TIARA trial at King’s College Hospital in London is now recruiting adult patients to trial a brand new potential treatment. Could you help? Find out if you could meet the criteria, and how to take part. Read more

Posted to: Research news and updates

Published: 15th May, 2023

Covid vaccination research is published in The Lancet Haematology

Covid vaccination research is published in The Lancet Haematology

We are very proud to announce that the recent Leeds Covid vaccination study, funded by The Aplastic Anaemia Trust, has been published today in The Lancet Haematology. Read more

Posted to: Research news and updates

Published: 30th June, 2022

Updated: 1st July, 2022

The AAT funds new research into COVID-19 vaccination responses in patients with aplastic anaemia and PNH

The AAT funds new research into COVID-19 vaccination responses in patients with aplastic anaemia and PNH

The new study will shed light on the question of how effective the Covid-19 vaccines are in aplastic anaemia patients. Read more

Posted to: Research news and updates

Published: 19th April, 2022

Do people with aplastic anaemia and/or PNH respond to the Covid-19 vaccines? Our research indicates, YES!

Do people with aplastic anaemia and/or PNH respond to the Covid-19 vaccines? Our research indicates, YES!

On December 6th, The Aplastic Anaemia Trust community received this update from the research team in Leeds about their study into the Covid-19 vaccine and people with aplastic anaemia and PNH. Watch the full presentation here! Read more

Posted to: Research news and updates

Published: 19th April, 2022

Update on the production of expanded autologous regulatory T cells to treat patients with refractory aplastic anaemia

Good progress made up until the Covid-19 crisis. Work set to resume once lockdown restrictions have been eased. Read more

Posted to: Research news and updates

Published: 1st June, 2020

Novel somatic mutations in aplastic anaemia patients

Novel somatic mutations in aplastic anaemia patients

Update on a project led by the researchers at King’s College Hospital/King’s College London, funded by the AAT, April 2020 Read more

Posted to: Research news and updates

Published: 1st June, 2020

Updated: 28th June, 2024

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Latest

  • Treatment to reduce your risk of infections

    Treatment to reduce your risk of infections

    Anti-microbial drugs that you may receive include antibiotics, anti-viral and antifungal drugs. They prevent and treat infections (infections which can be more dangerous for people with aplastic anaemia.)

  • Raising for the rare

    Running for Thomas!!! My son was diagnosed with Severe aplastic anemia in June 2025.

  • Young People's Support Group Taster Session

    Young People's Support Group Taster Session

    Are you aged 16-25, and affected by a rare bone marrow failure condition? If so, we'd love you to join us at our young people's support group taster session where we will help you to navigate stressful and uncertain times.

  • London Landmarks Half Marathon 2027

    London Landmarks Half Marathon 2027

    Join our 2027 London Landmarks Team! Spaces are limited and going fast so we recommend signing up now!

Most read

  • Covid Vaccination Updates

    Covid Vaccination Updates

    All of the latest updates about Covid vaccines and their impact on the AA community.

  • Treatment involving anti-thymocyte globulin (ATG)

    Treatment involving anti-thymocyte globulin (ATG)

    If you are an adult patient going into the hospital for ATG treatment, this fact sheet is for you

  • What is aplastic anaemia?

    What is aplastic anaemia?

    Aplastic means your bone marrow is failing to produce enough of all essential blood cells. Learn more about the condition, treatment, and how it impacts your life.

  • What is receiving ATG treatment like?

    What is receiving ATG treatment like?

    If you're reading this it means that you’re due to have your ATG treatment or have been told that this is the best treatment option for you. I’m going to share with you my own experience of having ATG.

  • Treatment with ciclosporin

    Treatment with ciclosporin

    Ciclosporin used as part of Anti-Thymocyte Globulin (ATG) treatment for adult patients

  • Diagnosis and treatment: a short summary

    Diagnosis and treatment information for adult patients. It worth noting that some of the main treatment options may also apply to young patients, however they will be treated by experts specialising in paediatric aplastic anaemia.

  • Get support

    Get support

    If you or someone you know has been diagnosed with aplastic anaemia or another rare bone marrow failure condition, we are here to help. No question is too big, or too small. Contact us online or give us a call.

  • Holidays and Travel

    Holidays and Travel

    How to plan a holiday when diagnosed with aplastic anaemia

  • Eltrombopag for the treatment of aplastic anaemia

    Eltrombopag for the treatment of aplastic anaemia

    Eltrombopag is one of the newer treatments for aplastic anaemia. You can find out more about it here.

  • Buffy's story

    Buffy's story

    This blog has been extremely hard for me to write...

Tag cloud

ATG Buffy Buffy Younger Impact Fund children diagnosis Elin's blog fundraising mental health Parents Positive stories Santa Splash stem cell transplant Super Rare video videos young people
Emotional Wellbeing support

Emotional Wellbeing support

Living with a rare bone marrow failure condition, or supporting someone who is can have a big impact on your emotional wellbeing. Our expert team are here to help you navigate these challenges and help you to feel less anxious and more in control. Read more

Published: 3rd January, 2024

Updated: 1st April, 2026

Author: Ellie Dawes

Register with The Aplastic Anaemia Trust

Register with The Aplastic Anaemia Trust

Are you living with aplastic anaemia, or a related condition like PNH, Fanconi anaemia, Dyskeratosis Congenita or Schwachman Diamond Syndrome? Or are you supporting a friend or family member who has? Please take a few minutes to register with us here. Read more

Published: 31st July, 2025

Updated: 4th February, 2026

Author: Ellie Dawes

Live in Wales? Write to your Senedd candidates and ask them to ensure patients have access to eltrombopag!

Live in Wales? Write to your Senedd candidates and ask them to ensure patients have access to eltrombopag!

On May 7th, the people of Wales go to the polls to elect new members of the Welsh Parliament. This election is an opportunity for those impacted by aplastic anaemia to raise the vital issue of fair access to medications for those living with rare diseases. Read more

Posted to: Research news and updates

Published: 7th April, 2026

Updated: 16th April, 2026

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